乐鱼-欧盟重新评估糖精及其钠、钾、钙盐作为食品添加剂的安全性

欧盟从头评估糖精和其钠、钾、钙盐作为食物添加剂的平安性时候：2024-11-18 10:30来历：食物火伴网作者： 泽夕 焦点提醒：2024年11月15日，据欧盟食物平安局（EFSA）动静，欧盟食物添加剂和调味剂小组（FAF）从头评估了糖精和其钠、钾、钙盐(E 954) 作为食物添加剂的平安性。 食物火伴网讯 2024年11月15日，据欧盟食物平安局（EFSA）动静，欧盟食物添加剂和调味剂小组（FAF）从头评估了糖精和其钠、钾、钙盐(E 954) 作为食物添加剂的平安性。 部门原文报导以下： This opinion deals with the re-evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives. Saccharin is the chemically manufactured compound 1,2-benzisothiazol-3(2H)-one-1,1-dioxide. Along with its sodium (Na), potassium (K) and calcium (Ca) salts, they are authorised as sweeteners (E 954). E 954 can be produced by two manufacturing methods i.e. Remsen-Fahlberg and Maumee. No analytical data on potential impurities were provided for products manufactured with the Maumee process; therefore, the Panel could only evaluate saccharins (E 954) manufactured with the Remsen-Fahlberg process. The Panel concluded that the newly available studies do not raise a concern for genotoxicity of E 954 and the saccharins impurities associated with the Remsen-Fahlberg manufacturing process. For the potential impurities associated with the Maumee process, a concern for genotoxicity was identified. The data set evaluated consisted of animals and human studies. The Panel considered appropriate to set a numerical acceptable daily intake (ADI) and considered the decrease in body weight in animal studies as the relevant endpoint for the derivation of a reference point. An ADI of 9 mg/kg body weight (bw) per day, expressed as free imide, was derived for saccharins (E 954). This ADI replaces the ADI of 5 mg /kg bw per day (expressed as sodium saccharin, corresponding to 3.8 mg /kg bw per day saccharin as free imide) established by the Scientific Committee on Food. The Panel considered the refined brand-loyal exposure assessment scenario the most appropriate exposure scenario for the risk assessment. The Panel noted that the P95 exposure estimates for chronic exposure to saccharins (E 954) were below the ADI. The Panel recommended the European Commission to consider the revision of the EU specifications of saccharin and its sodium, potassium and calcium salts (E 954). 本文由食物火伴网食物资讯中间编纂，供网友参考，有任何疑问，请联系news@foodmate.net。